CytomX teams up with Amgen to develop EGFR-targeting antibodies for cancer [Seeking Alpha]
CytomX Therapeutics, Inc. (CTMX)
Last cytomx therapeutics, inc. earnings: 11/7 04:09 pm
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Source: Seeking Alpha
CytomX teams up with Amgen to develop EGFR-targeting antibodies for cancerCytomX Therapeutics (NASDAQ:CTMX) inks astrategic collaboration with Amgen (NASDAQ:AMGN) to co-develop a CytomX Probody T-cell engaging bispecific against the well-validated cancer target Epidermal Growth Factor Receptor (EGFR).Probody T-cell engaging bispecifics are antibody constructs that the company says are capable of directing cytotoxic T cells in tumor microenvironments. In preclinical studies, CytomX's Probody versions of EGFRxCD3 bispecific therapeutics induced tumor regressions and increased the therapeutic window for the target.Under the terms of the partnership, the companies will co-develop a Probody T-cell engaging bispecific against EGFRxCD3. CytomX will lead early development with Amgen taking over later development and commercialization. Global late-stage development costs will be shared. Amgen will pay $40M upfront and purchase $20M of CTMX common stock. CytomX will be eligible for up to $455M
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CTMX
News
- CytomX Therapeutics, Inc. (NASDAQ: CTMX) was upgraded by analysts at JPMorgan Chase & Co. from an "underweight" rating to a "neutral" rating.MarketBeat
- CytomX Therapeutics Announces First Patient Dosed with CX-2051, a Conditionally Activated EpCAM-Directed ADC, in a Phase 1 Study in Patients with Advanced Solid Tumors [Yahoo! Finance]Yahoo! Finance
- CytomX Therapeutics Announces First Patient Dosed with CX-2051, a Conditionally Activated EpCAM-Directed ADC, in a Phase 1 Study in Patients with Advanced Solid TumorsGlobeNewswire
- CytomX Therapeutics Announces Nomination of Second Clinical Candidate in Broad PROBODY® T-Cell Engaging Bispecific (TCB) Collaboration with Astellas [Yahoo! Finance]Yahoo! Finance
- CytomX Therapeutics Announces Nomination of Second Clinical Candidate in Broad PROBODY® T-Cell Engaging Bispecific (TCB) Collaboration with AstellasGlobeNewswire
CTMX
Earnings
- 11/7/23 - Beat
CTMX
Sec Filings
- 4/4/24 - Form DEFA14A
- 4/4/24 - Form DEF
- 3/28/24 - Form 4
- CTMX's page on the SEC website