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Protagonist Therapeutics Initiates Phase 1 Study with Novel Hepcidin Mimetic, PTG-300

PROTAGONIST THERAPEUTICS (PTGX)  More Company Research Source: PR Newswire
US:NASDAQ Investor Relations: investors.protagonist-inc.com
PDF NEWARK, Calif., May 25, 2017 /PRNewswire/ -- Protagonist Therapeutics, Inc. (Nasdaq: PTGX) today announced that the company has initiated a Phase 1 clinical study of PTG-300 in normal healthy volunteers.  PTG-300 is an injectable hepcidin mimetic peptide discovered using the company's proprietary technology platform, and it is being developed as a potential treatment for patients with chronic iron overload in rare diseases such as beta-thalassemia. Hepcidin is a principal regulator of iron homeostasis in humans, and low levels of hepcidin may be associated with iron overload-related diseases such as thalassemia, myelodysplastic syndrome, and hereditary hemochromatosis. Iron overload can damage target organs and tissues including the bone marrow, liver, and heart leading to increased risks of anemia, liver disease, heart attack, heart failure, diabetes, and premature death. Beta-thalassemia is a rare, inherited blood disorder characterized by an underproduction o [Read more]

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