Adagene Announces First Patients With Advanced Non-Small Cell Lung Cancer Dosed In Phase 1b/2 Clinical Trial Of ADG106 In Combination With Nivolumab In Singapore [TheStreet.com]
Adagene Inc. - ADS, each representing 1.25 ordinary shares (ADAG)
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Source: TheStreet.com
SAN DIEGO and SUZHOU, China, Jan. 13, 2022 (GLOBE NEWSWIRE) -- Adagene Inc. ("Adagene") (Nasdaq: ADAG) today announced that the first patients have been dosed in a phase 1b/2 clinical trial of the anti-CD137 agonist antibody, ADG106, in combination with the anti-PD-1 antibody, Nivolumab for patients with advanced non-small cell lung cancer (NSCLC) who have progressed on prior therapies. The phase 1b/2 open label trial is designed to evaluate safety, tolerability, and anti-tumor activity of the combination in up to 53 patients with advanced NSCLC who have progressed after prior treatment. The trial will also include exploratory biomarker analyses of a novel predictive biomarker and immune cell profiling in response to the treatment. "This clinical trial is a key step in development of ADG106, which is being evaluated in combination with multiple anti-PD-1 therapies for synergistic T-cell stimulation that was shown in both preclinical and clinical studies in comparison with anti-CD137
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- Adagene Appoints Heinz-Josef Lenz, M.D., FACP to Scientific and Strategic Advisory Board [Yahoo! Finance]Yahoo! Finance
- Adagene Appoints Heinz-Josef Lenz, M.D., FACP to Scientific and Strategic Advisory BoardGlobeNewswire
ADAG
Sec Filings
- 3/29/24 - Form 6-K
- 3/29/24 - Form 424B5
- 3/29/24 - Form 20-F
- ADAG's page on the SEC website