Albireo's odevixibat shows encouraging action in mid-stage study [Seeking Alpha]
Albireo Pharma, Inc. (ALBO)
Last albireo pharma, inc. earnings: 3/2 07:30 am
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Source: Seeking Alpha
Albireo's odevixibat shows encouraging action in mid-stage study Albireo Pharma (NASDAQ: ALBO announces Pediatric cholestasis patients treated with odevixibat, an ileal bile acid transporter inhibitor, experienced reductions in serum bile acids as high as 92%. Two biliary atresia patients experienced reductions in serum bile acids of 58% and 51%. The two biliary atresia patients and most Alagille patients showed improvement in pruritis (itchy skin). On the safety front, odevixibat was generally well-tolerated. Two Alagille patients who had high baseline transaminase levels showed further further increases (biomarker for liver damage) so dosing was stopped at 200 ug. Topline data from a Phase 3 clinical trial, PEDFIC 1
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