Alder's eptinezumab shows treatment benefit in late-stage migraine study [Seeking Alpha]
ALDER BIOPHARMACEUTICALS INC (ALDR)
Last alder biopharmaceuticals inc earnings: 8/6 04:07 pm
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US:NASDAQ Investor Relations:
investor.alderbio.com/node/5806
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Source: Seeking Alpha
Alder's eptinezumab shows treatment benefit in late-stage migraine studyResults from a Phase 3 clinical trial, PROMISE 1, assessing Alder BioPharmaceuticals' (ALDR+0.4%) long-acting eptinezumab for the prevention of migraine showed a significant treatment effect. The data are being presented at the American Academy of Neurology Annual Meeting in Los Angeles.For months six through 12 (quarterly doses three and four), 70.7% of patients achieved an average 50% or greater reduction of migraine days from baseline compared to 58.7% for placebo. The results represented an 8.9% improvement from the reductions observed during the first and second quarterly doses.51.5% of patients achieved at least a 75% reduction in monthly migraine days from baseline versus 38.7% for placebo, a 12.8% improvement compared to the first two doses.On the safety front, the most common adverse events were upper respiratory infection (10.5%), common cold (6.8%) and sinusitis (3.6%).Eptinezumab is a monoclonal antibo
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