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Ascendis Pharma A/S Announces Dosing of Subjects in Phase 1 Trial of TransCon PTH

ASCENDIS PHARMA A/S AMERICAN D (ASND)  More Company Research Source: GlobeNewswire
Last ascendis pharma a/s american d earnings: 8/29 04:01 pm Check Earnings Report
US:NASDAQ Investor Relations: ascendispharma.com
PDF COPENHAGEN, Denmark, Sept. 26, 2017 (GLOBE NEWSWIRE) -- Ascendis Pharma A/S (Nasdaq:ASND), a biopharmaceutical company that utilizes its innovative TransCon technology to address significant unmet medical needs in rare diseases, announced today that it has dosed subjects in a phase 1 trial of TransCon PTH, a long-acting prodrug of parathyroid hormone (PTH) in development for the treatment of hypoparathyroidism. The single and multiple ascending dose phase 1 trial is designed to evaluate the safety, tolerability, pharmacodynamics, and pharmacokinetics of TransCon PTH in healthy adults. The trial evaluates single ascending doses and ten multiple daily doses of TransCon PTH. “This phase 1 trial will provide us key insights regarding the potential of TransCon PTH as a treatment for hypoparathyroidism. By replacing PTH at physiological levels, we have designed TransCon PTH to normalize serum and urinary calcium levels, as well as serum phosphate levels, and to improve quality of life,” [Read more]

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