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0 -0.00343583870361194 -0.00514521119297106 -0.00343583870361194 -0.000581186646382125 0.00179484111382718 0.00682039623254308 0.00511102374318381
Stock impact report

Aurinia And Voclosporin: Making A Difference In Focal Segmental Glomerulosclerosis [Seeking Alpha]

Aurinia Pharmaceuticals Inc - Common Shares (AUPH) 
Last aurinia pharmaceuticals inc - common shares earnings: 3/5 04:02 pm Check Earnings Report
US:NASDAQ Investor Relations: ir.auriniapharma.com
Company Research Source: Seeking Alpha
Summary There is no passion to be found playing small - Nelson Mandela Investment Thesis Aurinia Pharmaceuticals ( AUPH ) is a Canadian small-cap ($481M) biopharma that is establishing a name for itself in therapeutics for adult nephrotic diseases with the development of voclosporin ( formerly ISA247), a calcineurin inhibitor and a structural analog of cyclosporin A. Voclosporin, the lead investigative drug candidate, is in Phase 3 clinical trial for l upus nephritis and in Phase 2 clinical trials for dry eye syndrome including focal segmental glomerulosclerosis, the focus of this article . Voclosporin structurally and functionally differs from cyclosporin A. Voclosporin has been pharmacologically altered to exert a more potent and greater immunosuppressive efficacy and anti-inflammatory effects relative to cyclosporin A. Voclosporin also has reduced toxicity and more metabolic stability that accounts for its reduced variability in plasma concentration. These p Show less Read more
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