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Stock impact report

Blueprint Medicine down 9% premarket on early-stage BLU-667 data [Seeking Alpha]

Blueprint Medicines Corporation (BPMC) 
Last blueprint medicines corporation earnings: 2/13 07:00 am Check Earnings Report
US:NASDAQ Investor Relations: blueprintmedicines.com
Company Research Source: Seeking Alpha
Blueprint Medicine down 9% premarket on early-stage BLU-667 dataInvestors appear disappointed with Phase 1 data on Blueprint Medicines' (NASDAQ:BPMC) BLU-667 in RET-altered solid tumors. Shares are down9% premarket, albeit on light volume, on the heels of itsannouncement of the results, to be presented today at the American Association for Cancer Research Annual Meeting in Chicago.Data from the dose-escalation portion of the Phase 1 study, called ARROW, showed treatment with once-daily BLU-667 reduced tumors in 84% of patients with RET-altered cancer with measurable target lesions.The preliminary overall response rates (ORR) in patients with non-small cell lung cancer (NSCLC) and medullary thyroid cancer (MTC) were 50% and 40%, respectively. Across all evaluable patients, ORR was 45%.On the safety front, BLU-667 was well-tolerated with most adverse events (AEs) being mild or moderate. Grade 3 (serious) AEs occurring in two or more patients were hypertension and neutropenia. One patien Show less Read more
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