Cellectis: Approval of UCART123 Amendment in AML to Accelerate Clinical Development
Cellectis S.A. - American Depositary Shares (CLLS)
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Source: Business Wire
Increase of current tested dose levels from 6.25x104/kg to 2.5x105/kg Treatment interval shortens between patients from 42 days to 28 days, then to 14 days for subsequent patients MD Anderson Cancer Center added as new clinical site for the AML study NEW YORK--(BUSINESS WIRE)-- Regulatory News: Cellectis (Paris:ALCLS) (NASDAQ:CLLS) (Euronext Growth: ALCLS - Nasdaq: CLLS), a clinical-stage biopharmaceutical company focused on developing immunotherapies based on gene-edited allogeneic CAR T-cells (UCART), announced today the approval of an amendment to the protocol for the Phase 1 clinical trial of Cellectis’ UCART123 product candidate in patients with acute myeloid leukemia (AML). The main changes to the protocol include: Dose levels to be administered increase 400 percent from 6.25x104 to 2.5x105 UCART123 cells per kilogram, with a capping
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