Concert Pharmaceuticals Initiates Phase 1 Multiple-Ascending Dose Trial of CTP-692 as an Adjunctive Treatment for Schizophrenia
Concert Pharmaceuticals, Inc. (CNCE)
Last concert pharmaceuticals, inc. earnings: 4/30 07:00 am
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Source: Business Wire
LEXINGTON, Mass.--(BUSINESS WIRE)-- Concert Pharmaceuticals, Inc. (NASDAQ: CNCE) today announced that it has initiated an additional trial in the Phase 1 program evaluating CTP-692, a novel deuterium-modified form of D-serine being developed as an adjunctive treatment for schizophrenia. The Phase 1 multiple-ascending dose trial will evaluate the safety, tolerability, and pharmacokinetic profile of CTP-692 in healthy volunteers. Topline data from both the single-and multiple-ascending CTP-692 Phase 1 trials are expected in the second quarter of 2019. “The Phase 1 studies evaluating the dosing and safety of CTP-692 are expected to support advancement into an efficacy study in patients with schizophrenia later this year. D-serine is an important endogenous co-agonist of the NMDA receptor in humans which has been shown to be present at lower levels in the blood and cerebrospinal fluid in individuals wit
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