Dicerna Announces Results for PHYOX™4, Single-Dose Study of Nedosiran in Primary Hyperoxaluria Type 3 (PH3)
Dicerna Pharmaceuticals, Inc. (DRNA)
Last dicerna pharmaceuticals, inc. earnings: 2/27 04:05 pm
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Source: Business Wire
– Study Met Primary Safety Endpoint; Nedosiran Shown to be Generally Safe and Well Tolerated in Patients With PH3 –– Although Trial Did Not Meet Prespecified Secondary Efficacy Endpoint, Data Showed Encouraging Trends in Urinary Oxalate Reduction With Nedosiran Treatment –– Company on Track to Submit Nedosiran New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for Treatment of PH Type 1 (PH1) in Fourth Quarter of 2021 – LEXINGTON, Mass.--(BUSINESS WIRE)--Dicerna Pharmaceuticals, Inc. (Nasdaq: DRNA), a leading developer of investigational ribonucleic acid interference (RNAi) therapeutics, today announced top-line results from its PHYOX4 study designed to evaluate the safety and tolerability of a single subcutaneous dose of nedosiran, Dicerna’s late-stage investigational GalXC™ RNAi therapeutic candidate in development for primary hyperoxaluria (PH), compared to placebo in patients with PH type 3 (PH3). Nedosiran demonstrated safety and tolerability results in
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