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0.00111420612813388 0.00222841225626756 0.00083565459610031 0.00291364902506977 0.00334261838440124 0.0083565459610029 0.00612813370473554 0.0111420612813372
Stock impact report

BeiGene/SpringWorks doublet therapy shows encouraging action in preclinical studies [Seeking Alpha]

Epizyme, Inc. (EPZM) 
Last epizyme, inc. earnings: 2/24 06:30 am Check Earnings Report
US:NASDAQ Investor Relations: epizyme.com
Company Research Source: Seeking Alpha
Healthcare|On the MoveBeiGene/SpringWorks doublet therapy shows encouraging action in preclinical studiesJun. 22, 2020 11:09 AM ETBeiGene, Ltd. (BGNE)Douglas W. HouseBeiGene (-1.2%SWTX+1.5%positive preclinical dataPhase 1b/2Across a panel of RAS-mutated cancer models, clinically relevant concentrations of the drugs showed potent and synergistic activity. In two xenograft models (tissue transplanted from one species to another) the combo showed synergy as measured by pharmacodynamic pathway inhibition and tumor regression.The dose-escalation portion of the Phase 1b/2 trial should be completed by year-end. Dose-expansion cohorts, including patients with KRAS-positive non-small cell lung cancer and KRAS-positive endometrial cancer, will follow. Preliminary data should be presented at a medical conference in 2021.See all stocks on the move »Now read:FDA OK companion diagnostic for Epizyme's Tazverik » Show less Read more
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