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GALAPAGOS REPORTS PRIMARY ENDPOINT FOR THE ONGOING FILGOTINIB MANTA AND MANTA-RAy SAFETY STUDIES

Galapagos NV - American Depositary Shares (GLPG) 
Last galapagos nv - american depositary shares earnings: 10/24 04:01 pm Check Earnings Report
US:NASDAQ Investor Relations: glpg.com/company-overview
Company Research Source: GlobeNewswire
  8.3% patients on placebo and 6.7% patients on filgotinib had a 50% or more decline in sperm concentration at week 13No new safety findings were identifiedData will be submitted to the relevant regulatory authorities Mechelen, Belgium, 4 March 2021, 07.40 CET, regulated information –Galapagos NV (Euronext & Nasdaq: GLPG) today announced interim results from MANTA and MANTA-RAy, two ongoing safety studies investigating the effect of Jyseleca® (filgotinib) on sperm parameters in males with inflammatory bowel disease (MANTA) or rheumatic conditions (MANTA-RAy). In total, 248 patients were randomized 1:1 to receive filgotinib 200 mg once daily or placebo for an initial 13-week, double-blind treatment period. The primary endpoint in both trials was the proportion of patients who had a reduction of 50% or more in sperm concentration at Week 13. Patients who met this endpoint discontinued study treatment at Week 13, were switched to standard of care treatment and were monitored f Show less Read more
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