New Study Published in The American Journal of Pathology Suggests Obeticholic Acid (OCA) May Improve Cognitive Impairment Associated with Cholestatic Liver Disease
Intercept Pharmaceuticals, Inc. (ICPT)
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Source: GlobeNewswire
MORRISTOWN, N.J., Dec. 08, 2022 (GLOBE NEWSWIRE) -- Intercept Pharmaceuticals, Inc. (Nasdaq: ICPT), a biopharmaceutical company focused on the development and commercialization of novel therapeutics to treat progressive non-viral liver diseases, is pleased to share that The American Journal of Pathology has published results of a new study evaluating the link between cholestatic liver disease and cognitive impairment in mouse and human cell models. The study, which is the first to explore drug-based treatment response for cholestatic-related cognitive impairment, also evaluated the impact of anti-cholestatic therapies ursodeoxycholic acid (UDCA), obeticholic acid (OCA) and bezafibrate on their potential to reverse cognitive impairment and found that only OCA demonstrated potential efficacy. “Patients with liver disease at any stage often experience disruptive cognitive problems, such as difficulty concentrating and short-term memory loss, which can greatly impact quality of life,”
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