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Stock impact report

Immunocore falls 24% after early Phase 1 data for solid tumor candidate [Seeking Alpha]

Immunocore Holdings plc - American Depositary Shares (IMCR) 
Company Research Source: Seeking Alpha
Immunocore falls 24% after early Phase 1 data for solid tumor candidateSep. 09, 2022 10:30 AM ETImmunocore Holdings plc (IMCR)By:Dulan LokuwithanaSA News EditorluismmolinaU.K.-based biotech Immunocore Holdings plc (NASDAQ:A bi-specific protein basedon the IMCRâ??s therapeutic platform ImmTAC, IMC-F106C, is the companyâ??s first drug candidate to target the PRAME antigen in tumors.The data from the trial will be part of a presentation at the European Society for Medical Oncology (ESMO) Congress today.As of Jul. 18, 55 patients in 10 dose cohorts had received IMC-F106C, and the company said that the drug was well tolerated with well-manageable treatment-related adverse events, which were in line with the mechanism of action.However, the initial three doses were linked to cytokine release syndrome (CRS), mainly classified as Grade 1. None of the TRAEs led to trial discontinuations and death.Meanwhile, in terms of efficacy, 2/6 patients with cutaneous melanoma, 2/4 with ovarian cancer, an Show less Read more
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