Your Daily Pharma Scoop: ESPR Phase 3 Positive, FDA Rejects Volanesorsen, Ozempic Succeeds [Seeking Alpha]
Ionis Pharmaceuticals, Inc. (IONS)
Last ionis pharmaceuticals, inc. earnings: 2/26 07:00 am
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ionispharma.com
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Source: Seeking Alpha
Summary Stocks in News: ESPR Esperion announces positive results from phase 3 bempedoic acid/ezetimibe combination pill study Discussion: Positive top-line results from the pivotal Phase 3 trial of Esperion’s ( ESPR ) bempedoic acid/ezetimibe combination pill study ( 1002-053 ) has been reported by the company. This trial was conducted in a 380 high-risk patient group with maximally tolerated statins. The trial evaluated the efficacy and safety of the bempedoic acid 180 mg/ezetimibe 10 mg combination pill compared to bempedoic acid, ezetimibe or placebo. The trial met its key efficacy endpoint. The combination therapy reduced LDL-C at 12 weeks by 35%, and this clearly shows up against 3% reduction for placebo. The trial drug also clearly scores over 24% reduction shown by ezetimibe 10 mg (EZE) and 20% reduction shown by bempedoic acid 180 mg (BA). The fixed dose combination also showed a 34% reduction in high-sensitivity C-reactive protein (hsCRP)
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News
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- Ionis Pharmaceuticals, Inc. (NASDAQ: IONS) was upgraded by analysts at Wolfe Research from a "peer perform" rating to an "outperform" rating.MarketBeat
- Ionis Pharmaceuticals, Inc. (NASDAQ: IONS) had its "outperform" rating re-affirmed by analysts at William Blair.MarketBeat
IONS
Earnings
- 2/21/24 - Beat
IONS
Sec Filings
- 4/17/24 - Form 4
- 4/17/24 - Form 4
- 4/16/24 - Form 144
- IONS's page on the SEC website