I Still Can't Believe Juno Therapeutics Spent $46.4 Million on This Failed Drug [The Motley Fool]
JUNO THERAPEUTICS (JUNO)
Last juno therapeutics earnings: 11/1 04:05 pm
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Source: The Motley Fool
A costly learning exercise. Brian Orelli ( TMFBiologyFool ) May 25, 2017 at 4:21PM In March, Juno Therapeutics ( NASDAQ:JUNO ) announced that it was ending development of JCAR015 after five patients with acute lymphoblastic leukemia (ALL) died from cerebral edema -- brain swelling -- in its phase 2 clinical trial. The lethal side effect made it unlikely the treatment could get approved, despite extremely strong efficacy data. After a review of the data, the company said it thought there were protocol modifications and process improvements that would hopefully make JCAR015 safer, but those changes would require Juno to go back to phase 1. Since the biotech has other drug candidates to treat ALL, Juno made a decision with its partner Celgene ( NASDAQ:CELG ) that it would be best to shelve JCAR015 and focus on the other ALL therapies. All
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