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0.00110060759570007 0.00260828923364537 0.0071313341474814 -0.00191475568019066 0.00260828923364537 0.00336213005261802 0.00110060759570007 0.0161774239751533
Stock impact report

Karyopharm: Another 2 Year Wait For Data [Seeking Alpha]

Karyopharm Therapeutics Inc. (KPTI) 
Last karyopharm therapeutics inc. earnings: 2/13 07:00 am Check Earnings Report
US:NASDAQ Investor Relations: investors.karyopharm.com/investor-relations
Company Research Source: Seeking Alpha
shapecharge/E+ via Getty ImagesI haven't covered Karyopharm Therapeutics Inc. (NASDAQ:KPTIthe last 11 months. I willquoteall those 8 reasons, and then focus on those still relevant:One, the company had earlier said it will submit an NDA in liposarcoma in Q1 2021; however, despite positive data from SEAL, it didn't. Two, XPOVIO's (selinexor) Q4 2020 sales were less than stellar, and QoQ uptake of the drug hasn't progressed by a large percentage. Three, a number of competing drugs have emerged in some of the indications where XPOVIO is approved. Four, the SIENDO trial readout in endometrial cancer, probably the molecule's most high-potential indication, is still two quarters away, and the market isn't keeping focus on SIENDO. Five, the market must still be worried about selinexor's toxicity profile, recalling the nightmarish scenario surrounding its original approval for penta-refractory multiple myeloma, in 2019. Six, insiders hate the stock - they have always sold, and never bought, b Show less Read more
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