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Kymera Therapeutics to Present Pre-clinical Data at the EULAR 2022 Congress Showing STAT3 Degradation Blocked Th17 Development and Prevented Rheumatoid Arthritis

Kymera Therapeutics, Inc. (KYMR) 
Company Research Source: GlobeNewswire
WATERTOWN, Mass., June 01, 2022 (GLOBE NEWSWIRE) -- Kymera Therapeutics, Inc. (NASDAQ: KYMR), a clinical-stage biopharmaceutical company advancing targeted protein degradation to deliver novel small molecule protein degrader medicines, will present new preclinical data demonstrating that STAT3 degradation blocked Th17 development and cytokine release and prevented collagen-induced arthritis (CIA), a pre-clinical model of rheumatoid arthritis, today at the EULAR 2022 Congress in Copenhagen, Denmark. “These data further establish proof-of-concept for Kymera’s potent and selective STAT3 degraders in inflammatory and autoimmune disorders,” said Anthony Slavin, Vice President, Immunology. “Our findings demonstrate that even limited degradation of STAT3 results in significant suppression of proinflammatory cytokines across several immune cell types, including monocytes and T cells. The ability to block Th17 development and cytokine release with STAT3 degradation, and the demonstration Show less Read more
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