Sermonix Pharmaceuticals Completes Enrollment of Phase 2 ELAINE 1 Randomized Clinical Trial Assessing Efficacy of Oral Lasofoxifene Versus Intramuscular Fulvestrant
Ligand Pharmaceuticals Incorporated (LGND)
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Source: GlobeNewswire
COLUMBUS, Ohio, Aug. 16, 2021 (GLOBE NEWSWIRE) -- Sermonix Pharmaceuticals Inc., a privately held biopharmaceutical company developing innovative therapeutics to treat ESR1-mutated metastatic breast and gynecological cancers, today announced that it has completed enrollment in its Phase 2 randomized clinical trial studying the efficacy of its lead investigational drug, lasofoxifene, versus fulvestrant for the treatment of ER+/HER2- breast cancer in patients with an ESR1 mutation. Sermonix expects data from the trial to be reported in the first half of 2022. The open-label, multi-center Evaluation of Lasofoxifene in ESR1 Mutations (ELAINE 1, NCT03781063) study is evaluating the efficacy of oral lasofoxifene versus intramuscular fulvestrant for the treatment of 100 postmenopausal women with locally advanced or metastatic estrogen receptor-positive ER+/HER2- breast cancer with an ESR1 mutation and progression-free survival as the primary endpoint. “The completion of ELAINE 1 enro
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