Leap Therapeutics Announces Collaboration With EORTC to Evaluate DKN-01 in Combination with PD-L1 Cancer Immunotherapy and Chemotherapy In Esophagogastric and Biliary Tract Cancers
Leap Therapeutics, Inc. (LPTX)
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Source: GlobeNewswire
CAMBRIDGE, Mass., Sept. 08, 2017 (GLOBE NEWSWIRE) -- Leap Therapeutics, Inc. (NASDAQ:LPTX), a biotechnology company developing targeted and immuno-oncology therapeutics, today announced an immunotherapy collaboration with the European Organisation for Research and Treatment of Cancer (EORTC). The cooperative group sponsored clinical trial will evaluate DKN-01 in combination with atezolizumab (TECENTRIQ®) +/- paclitaxel in advanced esophagogastric malignancies and DKN-01 + atezolizumab in advanced biliary tract cancers at EORTC centers across Europe. Roche will supply atezolizumab to the EORTC for this study collaboration. “DKN-01 has shown promising activity in advanced esophagogastric and biliary tract cancers. Given the emerging role of Wnt/beta-catenin in immuno-oncology, we believe that DKN-01 could be a novel immunotherapy for these patients and look forward to evaluating its activity when combined with atezolizumab and paclitaxel,” commented Markus Moehler, M.D., Ph.D, Profes
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