Lexicon Pharmaceuticals Announces Positive 52-Week Results From Sotagliflozin inTandem2 Study Presented at ADA 2018 and Published in Diabetes Care
Lexicon Pharmaceuticals, Inc. (LXRX)
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Source: GlobeNewswire
Sotagliflozin, in Combination with Insulin, Significantly Decreased A1C Levels and Reduced Weight at 52 Weeks Results Observed at 24 Weeks Persisted at 52 Weeks THE WOODLANDS, Texas, June 23, 2018 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq:LXRX), today announced positive 52-week results from the Phase 3 inTandem2 study for sotagliflozin in adults with type 1 diabetes. In the European study, sotagliflozin 200 mg or 400 mg in combination with maximally tolerated standard of care insulin therapy demonstrated statistically significant reductions in A1C levels and weight compared to optimized insulin alone. A lower incidence of severe hypoglycemia was observed with sotagliflozin 400 mg compared to placebo. Improvements in certain elements of glycemic control beyond A1C were also observed, including fasting plasma glucose (FPG) and glycemic variability. The results were unveiled today as part of a moderated poster discussion at the 78th Scientific Sessions of the
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- Clinical Data on the Impact of Sotagliflozin on Stroke and Heart Attack Risk Among Four Lexicon-Sponsored Presentations at the American College of Cardiology 73rd Annual Scientific Session & Expo [Yahoo! Finance]Yahoo! Finance
- Clinical Data on the Impact of Sotagliflozin on Stroke and Heart Attack Risk Among Four Lexicon-Sponsored Presentations at the American College of Cardiology 73rd Annual Scientific Session & ExpoGlobeNewswire
- Lexicon (LXRX) Dips on Post Hoc Analysis Data on Sotagliflozin [Yahoo! Finance]Yahoo! Finance
- New Post Hoc Analysis of inTandem3 Study Demonstrates Improvements In Glycemic Control With Sotagliflozin Treatment in Patients With Type 1 Diabetes and Chronic Kidney Disease [Yahoo! Finance]Yahoo! Finance
- New Post Hoc Analysis of inTandem3 Study Demonstrates Improvements In Glycemic Control With Sotagliflozin Treatment in Patients With Type 1 Diabetes and Chronic Kidney DiseaseGlobeNewswire
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