Madrigal’s MGL-3196 Achieves Liver Biopsy Endpoints in Patients with Non-alcoholic Steatohepatitis (NASH) at 36 Weeks in Phase 2 Clinical Trial
Madrigal Pharmaceuticals, Inc. (MDGL)
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Source: GlobeNewswire
-- Statistically significantly more patients treated with MGL-3196 compared with placebo treated patients achieved a two point reduction in NAS (NAFLD activity score) on biopsy -- -- Statistically significantly more patients treated with MGL-3196 compared with placebo treated patients achieved resolution of NASH on biopsy -- -- A =30% fat reduction (MRI-PDFF) in MGL-3196 treated patients, at Week 12 predicted an improved NASH histologic response at Week 36, including 39% NASH resolution, which was statistically significant relative to placebo -- -- MGL-3196 was well-tolerated with mostly mild and a few moderate AEs; 7 SAEs, none drug related, none occurring more than once, 5 in MGL-3196, 2 in placebo-treated patients (study randomized 2:1) -- -- Conference call scheduled for 8:30 AM Eastern Time today -- CONSHOHOCKEN, Pa., May 31, 2018 (GLOBE NEWSWIRE) -- Madrigal Pharmaceuticals, Inc. (Nasdaq:MDGL) today announced positive top-line, 36-week results from a Phase 2 clinical tria
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