Mesoblast and JCR Pharmaceuticals Expand Japan License Agreement to Use of Mesenchymal Stem Cells in Newborns With Insufficient Blood Flow to the Brain
Mesoblast Limited - American Depositary Shares (MESO)
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Source: GlobeNewswire
NEW YORK and MELBOURNE, Australia, June 11, 2019 (GLOBE NEWSWIRE) -- Mesoblast Limited (ASX:MSB; Nasdaq:MESO) today announced it has expanded its partnership with JCR Pharmaceuticals Co. Ltd. in Japan to the use of mesenchymal stem cells (MSCs) for the treatment of newborns who lack sufficient blood supply and oxygen to the brain, a condition termed neonatal hypoxic ischemic encephalopathy (HIE). HIE occurs in 2.5 per 1,000 live births1 and can cause seizures, delayed development of motor skills and cognitive function, and cerebral palsy2. In preclinical studies, MSCs have been shown to have a significant positive effect on neurobehavioral outcome following HIE injury3. JCR is marketing the allogeneic MSC product TEMCELL®4 HS Inj. for the treatment of steroid-refractory acute graft versus host disease (aGVHD) in children and adults in Japan. Under the terms of the partnership, Mesoblast receives royalties on TEMCELL product sales for all licensed indications. The license agreeme
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