Momenta Pharmaceuticals Announces Publication of New Data Supporting M281 as First Anti-FcRn Antibody to Inhibit Maternal-Fetal IgG Transfer in the Human Term Placenta
MOMENTA PHARMACEUTICALS (MNTA)
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Source: GlobeNewswire
Data supports M281’s potential to prevent placental transfer of disease-inducing antibodies from mother to fetus in alloimmune and autoimmune diseases of the fetus and newborn Global multi-center Phase 2 study of M281 in hemolytic disease of the fetus and newborn (HDFN) now active following regulatory approvals CAMBRIDGE, Mass., March 21, 2019 (GLOBE NEWSWIRE) -- Momenta Pharmaceuticals, Inc. (Nasdaq: MNTA), a biotechnology company focused on discovering and developing novel biologic therapeutics to treat rare immune-mediated diseases, today announced new preclinical data for M281, its potentially best-in-class anti-FcRn antibody, was published in the American Journal of Obstetrics & Gynecology. The data show that M281 inhibits maternal to fetal IgG transfer in the human ex vivo term placental perfusion model, while showing minimal transfer itself to fetal circulation. The published study entitled, “M281, an anti-FcRn antibody, inhibits IgG transfer in a human ex vivo placental
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