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'Tumor agnostic' cancer drugs seen boosting wider genetic tests [Reuters]

MERCK (MRK)  More Company Research Source: Reuters
Last merck earnings: 5/1 06:45 am Check Earnings Report
US:NYSE Investor Relations: investors.merck.com/home/default.aspx
PDF 'Tumor agnostic' cancer drugs seen boosting wider genetic tests CHICAGO New cancer drugs that target genetic mutations regardless of where the tumor is growing should expand the practice of testing patients for such glitches, oncology experts say. Such "tumor-agnostic" drugs from companies including Merck & Co and Loxo Oncology may help overcome misgivings by health insurers, who have balked at covering large-scale tests looking for genetic mutations in tumors, and quell concerns of some top cancer doctors who question whether enough patients benefit from such tests. Last month, Merck's immunotherapy Keytruda became the first cancer treatment ever to win U.S. approval based on whether the tumor carried a specific genetic glitch, irrespective of the tumor's location. More recently, Loxo showed that its drug larotrectinib helped shrink tumors in 76 percent of patients with a wide variety of advanced cancers who carried a specific genetic defect. The surprising results suggested a benef [Read more]

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