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NuCana Announces Promising Clinical Data at ASCO GI on NUC-1031 (Acelarin®) as Front-Line Treatment of Advanced Biliary Tract Cancer

NuCana plc - American Depositary Shares (NCNA) 
Last nucana plc - american depositary shares earnings: 3/10 04:02 pm Check Earnings Report
US:NASDAQ Investor Relations: nasdaq.com/symbol/ncna/historical
Company Research Source: GlobeNewswire
EDINBURGH, United Kingdom, Jan. 19, 2018 (GLOBE NEWSWIRE) -- NuCana plc (NASDAQ:NCNA) announced interim results today from the ABC-08 Study at the 2018 ASCO Gastrointestinal Cancer Symposium (ASCO GI) in San Francisco, CA.  This analysis of the Phase 1b multi-center, open-label study showed that Acelarin, when combined with cisplatin, achieved high response rates and was well-tolerated in front-line advanced biliary tract cancer. Eight patients with advanced biliary tract cancer received Acelarin (625mg/m2) and cisplatin (25mg/m2) on days one and eight of a three-week cycle.  A Complete Radiological Response was achieved in one patient, a Partial Response in three patients, and Stable Disease in one patient, resulting in an Objective Response Rate of 50% and a Disease Control Rate of 63% on an intent-to-treat basis.  Additionally, the one patient with Stable Disease, whose cancer initially had been considered unsuitable for surgical resection, went on to have surgery to remove the Show less Read more
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