Alzheimer's Pathways: An Investor's Guide To Biogen, Anavex, And Neurotrope [Seeking Alpha]
NextTrip, Inc. (NTRP)
NASDAQ:AMEX Investor Relations:
neurotropebioscience.com/welcome_to_neurotrope_bioscience/investorsrelations.html
Company Research
Source: Seeking Alpha
Summary At the recent CTAD conference in Barcelona, Spain a number of companies presented new data regarding their Alzheimer’s drug candidates. Much of the attention focused on Biogen ( BIIB ), but other companies may be pursuing more fruitful strategies against Alzheimer’s disease. In many cases, results reflect the likely mechanisms of the disease whether its Biogen’s efforts to remove amyloid oligomers, Anavex’s ( AVXL ) focus on inhibiting intracellular calcium release, or Neurotrope’s ( NTRP) hopes founded on the activation of protein kinase C. To a degree, each company’s efforts are linked to the chain of events that leads to the onset and progression of Alzheimer’s disease. The above chart ( glutamate neurotoxicity ) and this linked diagram ( KEGG pathway Alzheimer's disease ) likely provide many of the critical pathways that can result in the development of Alzheimer’s disease. The role of amyloid oligomers in these pathways is highlighted in the f
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