Aegis Awarded Patent for Fast Acting Nasal Spray Opioid Blockers and Pain Medications
Opiant Pharmaceuticals, Inc. (OPNT)
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Source: GlobeNewswire
SAN DIEGO, Feb. 22, 2018 (GLOBE NEWSWIRE) -- Aegis Therapeutics LLC announced today that it has been awarded U.S. Patent No. 9,895,444 providing non-invasive metered nasal spray delivery of multiple opioid blockers such as nalmefene, naltrexone, methylnaltrexone and naloxone for rescue therapy in opioid overdose, as well as opioid pain medications such as morphine, buprenorphine, and nalbuphine, among others. In early February it was reported by Aegis’ exclusive worldwide licensee for nalmefene, naloxone, and naltrexone, Opiant Pharmaceuticals Inc. (NASDAQ:OPNT), that the National Institute on Drug Abuse (NIDA) conducted a Phase I nasal nalmefene study under a clinical trial agreement with Opiant. The study demonstrated that an intranasal nalmefene formulation containing Aegis’ proprietary absorption enhancer (Intravail®) resulted in rapid increases in plasma levels with an onset faster than an intramuscular injection and a comparatively long half-life (6.7-7.8 hours). Earlier Op
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