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0 -0.00359712230215836 -0.0683453237410072 -0.140287769784173 -0.136690647482015 -0.111510791366906 -0.154712230215827 -0.118741007194245
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Phio Pharmaceuticals Presents Positive In Vivo Data at ASGCT Showing PH-762 Significantly Enhanced Antitumor Efficacy of HER2-Targeted CAR-T Cells

Phio Pharmaceuticals Corp. (PHIO) 
Last phio pharmaceuticals corp. earnings: 11/12 07:45 am Check Earnings Report
Company Research Source: PR Newswire
MARLBOROUGH, Mass., May 11, 2021 /PRNewswire/ -- Phio Pharmaceuticals Corp. (Nasdaq: PHIO), a biotechnology company developing the next generation of immuno-oncology therapeutics based on its proprietary self-delivering RNAi (INTASYL™) therapeutic platform, today announced positive new in vivo data showing that PH-762 significantly enhanced the antitumor efficacy of HER2-targeted CAR-T cells (HER2CART) in solid tumors. Compared to untreated HER2CART cells, HER2CART cells treated with PH-762 showed a statistically significant and durable inhibition of tumor growth. These data, using a HER2-targeted CAR-T cell product against a HER2-expressing ovarian cancer xenograft model, provide proof-of-concept for the application of PD-1 checkpoint silencing with INTASYL in CAR-T cells prior to adoptive cell therapy to enhance the therapeutic efficacy of CAR-T cell therapy in solid tumors. Logo - https://mma.prnewswire.com/media/786567/Phio_Pharmaceuticals_Logo.jpg   "The in vivo data announced to Show less Read more
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