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0.0675675675675676 0.148648648648649 0.0945945945945947 0.0810810810810812 0.0270270270270271 0.0810810810810812 0.0335810810810811 -0.0337837837837837
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Sonnet BioTherapeutics Announces Progress in Two Phase 1 Dose-Escalation Trials of SON-1010

Sonnet BioTherapeutics Holdings, Inc. (SONN) 
Company Research Source: Accesswire
The SB101 and SB102 studies have together dosed 19 subjects to dateThis early review of safety sets the stage for further dose escalationAdditional safety and cytokine-specific data are expected during the fourth calendar quarter of 2022PRINCETON, NJ / ACCESSWIRE / September 21, 2022 / Sonnet BioTherapeutics Holdings, Inc., (NASDAQ:SONN) a clinical-stage company developing targeted immunotherapeutic drugs, announced today that initial safety has been formally reviewed in both Phase 1 clinical trials of SON-1010(IL12-FHAB) in adults and that dose escalation is continuing. SB101 is a multiple-dose trial for patients with advanced solid tumors that commenced in April (NCT05352750) and has now started treating the third dose cohort. SB102 is a single-ascending dose trial in healthy volunteers (NCT05408572) that started in July and is dosing the second cohort. Safety Review Committees met to discuss the findings after each cohort, found no safety concerns to prevent moving forward, and app Show less Read more
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