Early-stage study of combination of Aduro's ADU-S100 and Novartis' PDR001 underway [Seeking Alpha]
ADURO BIOTECH (ADRO)
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Early-stage study of combination of Aduro's ADU-S100 and Novartis' PDR001 underwayThe first patient has beendosed in aPhase 1b clinical trial assessing the combination of Aduro Biotech's (ADRO-0.9%) STING pathway activator ADU-S100 and Novartis' (NVS-0.9%) PD-1 checkpoint inhibitor PDR001 in ~175 patients with advanced/metastatic solid tumors or lymphomas.According to ClinicalTrials.gov, the estimated completion date is February 2020.Aduro says STING is generally expressed at high levels in immune cells and, once activated, initiates a profound innate immune response through multiple pathways.Aduro and Novartis are working together under their March 2015 collaboration agreement.Previously:Novartis teams up with Aduro Biotech in cancer immunotherapy (March 30, 2015)Now read:Novartis: Dividend Aristocrat But Pressure From Generics And Drug Trial Failures May Overwhelm »
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