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Stock impact report

Affimed's lead candidate shows treatment benefit in early-stage study; investors unimpressed, shares down 27% [Seeking Alpha]

Affimed N.V. (AFMD) 
Last affimed n.v. earnings: 11/19 07:30 am Check Earnings Report
US:NASDAQ Investor Relations: affimed.com/investor-relations.php
Company Research Source: Seeking Alpha
Affimed's lead candidate shows treatment benefit in early-stage study; investors unimpressed, shares down 27%Thinly traded nano cap Affimed N.V. (AFMD-26.9%) slumps on more than a 4x surge in volume on the heels of itsannouncement of interim results from aPhase 1b clinical trial assessing lead candidate AFM13 combined with Merck's KEYTRUDA (pembrolizumab) in patients with relapsed/refractory Hodgkin lymphoma (HL). The data were presented at ASH in Atlanta.Patients receiving the combination experienced an 83% (n=5/6) overall response rate (ORR), above the historical ORR of 58 - 63% for KEYTRUDA alone.On the safety front, one dose-limited toxicity was observed in cohort 3 (the highest dose 7.0 mg/kg) which was an infusion reaction leading to discontinuation. Four Grade 3 (serious) adverse events were reported, three possibly related to AFM13 and KEYTRUDA: nausea, vomiting and the infusion-related reaction.Investors appear disappointed with the slow pace of the 33-subject study. Accordin Show less Read more
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