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Stock impact report

Oncology Could Give Gutsy Biotechs Another Chance [Seeking Alpha]

Seres Therapeutics, Inc. (MCRB) 
Last seres therapeutics, inc. earnings: 11/5 07:00 am Check Earnings Report
US:NASDAQ Investor Relations: ir.serestherapeutics.com
Company Research Source: Seeking Alpha
Companies focusing on the gut microbiome were dealt a serious blow last year with Seres’ (NASDAQ: MCRB ) phase II failure, but now a small study could reinvigorate the field. The trial looks like the first to show in humans that response to the anticancer checkpoint blockade could be determined by the composition of patients’ gut bacteria. Most biotech start-ups in this field have focused on more obvious applications, like treating bacterial and gastrointestinal diseases – strategies that have brought in over $600m of financing (see table below). But immuno-oncology offers a new avenue, and two players, Synlogic and Evelo Biosciences, already have an early focus here. Of course, a link between the microbiome – the genetic makeup of the microbes in the human body – and diseases from asthma to multiple sclerosis has been postulated for some time. But its role in cancer immunotherapy, while intriguing, was a very early hypothesis. Indeed, the only recent evidence backing it Show less Read more
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