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0.318518518518518 0.318518518518518 0.162962962962963 0.111111111111111 0.0592592592592591 -0.00740740740740741 -0.0148148148148148 -0.0182962962962963
Stock impact report

Ganaxolone Reduces Seizures and Improves Behaviors in Angelman Syndrome Preclinical Model

Marinus Pharmaceuticals, Inc. (MRNS) 
Last marinus pharmaceuticals, inc. earnings: 11/6 07:30 am Check Earnings Report
US:NASDAQ Investor Relations: ir.marinuspharma.com/investor-relations
Company Research Source: GlobeNewswire
Data Published in NeuropharmacologyRADNOR, Pa., Feb. 14, 2017 (GLOBE NEWSWIRE) -- Marinus Pharmaceuticals, Inc. (Nasdaq:MRNS), a biopharmaceutical company dedicated to the development of innovative therapeutics to treat epilepsy and neuropsychiatric disorders, today announced the publication of preclinical data in the January issue of Neuropharmacology, showing that its positive allosteric modulator of GABAA, ganaxolone ameliorates many of the behavioral abnormalities in a  mouse model of adult Angelman syndrome (AS). Evidence from experimental models suggests that AS may be associated with deficient extrasynaptic GABAA receptor function. AS is a rare neurogenetic disorder characterized by severe developmental delay, motor impairments and epilepsy. The published article, co-authored by, among others, Michael A. Rogawski, M.D., Ph.D, professor of neurology and pharmacology at the School of Medicine, University of California, Davis, and titled “Effects of the synthetic neurosteroid ga Show less Read more
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