Ziopharm Oncology Announces Publication of Positive Results of Phase 1 Monotherapy Trial of Controlled IL-12 in Patients with Recurrent Glioblastoma in Science Translational Medicine
ZIOPHARM Oncology Inc (ZIOP)
Last ziopharm oncology inc earnings: 3/2 04:05 pm
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Source: GlobeNewswire
– Ad-RTS-hIL-12 plus 20 mg veledimex (Controlled IL-12 platform) determined to be the preferred dose with low-dose steroids to treat adult patients with recurrent glioblastoma –– Median overall survival for Controlled IL-12 in patients receiving low-dose steroids was 17.8 months – – Increased tumor infiltrating lymphocytes and PD-1 (programmed cell death protein 1) support immunological anti-tumor effect of Controlled IL-12 – BOSTON, Aug. 14, 2019 (GLOBE NEWSWIRE) -- Ziopharm Oncology, Inc. (“Ziopharm” or the “Company”) (Nasdaq: ZIOP), today announced the publication of its phase 1 trial of Controlled IL-12 in patients with recurrent glioma in the journal Science Translational Medicine. The publication entitled, “Regulatable interleukin 12 gene therapy in patients with recurrent high-grade glioma: results of a phase 1 trial” can be accessed at https://stm.sciencemag.org/. While IL-12 is known as a potent immune activator that triggers T cells to target cancer, historic trials sy
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