Gilead Announces Phase 2 Results for GS-0976 in Nonalcoholic Steatohepatitis (NASH)
Gilead Sciences, Inc. (GILD)
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Source: Business Wire
- Oral ACC Inhibitor Led to Significant Reductions in Measures of Liver Fat and Fibrosis - - Results from the GS-0976 Phase 2 Study and 18 Other Abstracts from Across Gilead’s Liver Fibrosis Pipeline Presented at The Liver Meeting® 2017 - WASHINGTON--(BUSINESS WIRE)-- Gilead Sciences, Inc. (Nasdaq: GILD) today announced results from a Phase 2, randomized, placebo-controlled trial evaluating two doses of GS-0976, an oral, investigational inhibitor of Acetyl-CoA carboxylase (ACC), in patients with nonalcoholic steatohepatitis (NASH). The data demonstrate that the higher dose of GS-0976 (20 mg taken orally once daily) when administered for 12 weeks was associated with statistically significant reductions in hepatic steatosis (buildup of fat in the liver) and a noninvasive marker of fibrosis (TIMP-1) compared to placebo. These results are being presented during a late-breaking abstract session a
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