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0 0.00191938579654506 0 0.00191938579654506 -0.0115163147792707 -0.0211132437619962 -0.0211132437619962 -0.0211132437619962
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AbCellera Presents Data Showing Preclinical Efficacy of PSMA x CD3 T-Cell Engagers at AACR 2025

AbCellera Biologics Inc. - Common Shares (ABCL) 
Company Research Source: Business Wire
Preclinical data on AbCellera’s PSMA x CD3 T-cell engagers demonstrate potent anti-tumor activity and potential to further enhance function through costimulatory strategies VANCOUVER, British Columbia--(BUSINESS WIRE)--AbCellera (Nasdaq: ABCL) today announced new data on its PSMA x CD3 T-cell engagers (TCEs), presented as a poster at the American Association for Cancer Research? (AACR) 116th Annual Meeting at the McCormick Place Convention Center in Chicago, Illinois, taking place April 25 to 30, 2025.Targeting prostate-specific membrane antigen (PSMA) with a CD3 TCE could provide an effective treatment option for metastatic castration-resistant prostate cancer (mCRPC). In its poster presentation at AACR, AbCellera demonstrated that its PSMA x CD3 TCEs show promising preclinical activity, including:Potent in vitro tumor-cell killing, with one molecule showing ~10x higher EC50 than benchmarkSustained in vitro activity across four rounds of serial T-cell killingPreclinical in vivo ef Show less Read more
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