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Stock impact report

Roche Alzheimer's drug fails, joining long list of trial flops [Reuters]

AC Immune SA (ACIU) 
Last ac immune sa earnings: 11/13 07:00 am Check Earnings Report
US:NASDAQ Investor Relations: acimmune.com/en/investors
Company Research Source: Reuters
Roche Alzheimer's drug fails, joining long list of trial flops By Reuters Staff 2 Min Read ZURICH (Reuters) - An experimental Alzheimer’s drug from Roche and AC Immune failed to slow cognitive and functional decline in a trial, the Swiss companies said on Wednesday, in a fresh setback to efforts to fight the fatal dementia-causing disease. AC Immune boss Andrea Pfeifer described the results of the trial of semorinemab as “surprising and disappointing”. The drug targets “tau” proteins believed to play a role in Alzheimer’s and offers an alternative to treatments aiming to fight amyloid beta peptides in the brain. The outcome of the Phase 2 trial - in patients with an early stage of Alzheimer’s - means the failure rate for drugs aiming to fight the brain-wasting illness, which afflicts tens of millions of people worldwide, remains at nearly 100%. “We believe the full data analysis of this first-of-its-kind study will yield information about this promising target that will advance our u Show less Read more
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