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Stock impact report

Gilead to buy Ouro Medicines for up to $2.2 billion [Yahoo! Finance]

Arcellx, Inc. (ACLX) 
Company Research Source: Yahoo! Finance
biotechnology company focused on developing T cell engager therapies for autoimmune diseases. The acquisition will cost Gilead $1.675 billion in upfront cash consideration, subject to customary adjustments, plus up to $500 million in contingent milestone payments. The deal adds OM336 (gamgertamig), a clinical-stage BCMAxCD3 T cell engager, to Gilead's inflammation portfolio. OM336, which has gotten both Fast Track and Orphan Drug Designation, is designed to enable rapid B cell depletion following subcutaneous treatment. In ongoing Phase 1/2 clinical studies, the drug has shown efficacy in severe autoimmune diseases including autoimmune hemolytic anemia and immune thrombocytopenia. Gilead plans to enter into a strategic collaboration with Galapagos on the Ouro portfolio. Under the proposed arrangement, Galapagos would pay 50% of the upfront consideration and milestone payments, absorb substantially all of Ouro's operating assets and retain its employees. Galapagos would be respon Show less Read more
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