Aclaris Therapeutics Announces Phase 2 Clinical Trial of ATI-502 Topical in Patients with Alopecia Areata Did Not Meet Endpoints
Aclaris Therapeutics, Inc. (ACRS)
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Source: GlobeNewswire
ATI-502 did not achieve statistical superiority at the primary or secondary endpoints due to high rates of disease resolution in vehicle-treated patients WAYNE, Pa., June 26, 2019 (GLOBE NEWSWIRE) -- Aclaris Therapeutics, Inc. (NASDAQ: ACRS), a physician-led biopharmaceutical company focused on immuno-inflammatory diseases, today announced results from a Phase 2 clinical trial of ATI-502 (AA-201 Topical), an investigational topical Janus Kinase (JAK) 1/3 inhibitor, in patients with alopecia areata (AA). ATI-502 did not achieve statistical superiority at the primary or secondary endpoints due to high rates of disease resolution in vehicle-treated patients. AA-201 Topical, a Phase 2 randomized, double-blinded, parallel-group, vehicle-controlled trial, evaluated the safety, efficacy, and dose response of two concentrations of ATI-502, 0.12% and 0.46%, on the regrowth of hair in 129 subjects with AA. Subjects applied ATI-502 to their scalp twice daily for 24 weeks. The primary endpoi
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ACRS
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- 2/27/24 - Beat
ACRS
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- 4/25/24 - Form ARS
- 4/25/24 - Form DEFA14A
- 4/25/24 - Form DEF
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