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-0.0182767624020887 -0.0156657963446475 0.010443864229765 0.010443864229765 0.0026109660574412 -0.0339425587467363 0.0169712793733681 0.010443864229765
Stock impact report

Aclaris Therapeutics' Novel ITK/JAK3 Inhibitor ATI-2138 Demonstrates Rapid and Sustained Hair Regrowth in Validated Murine Model of Alopecia Areata (AA) [Yahoo! Finance]

Aclaris Therapeutics, Inc. (ACRS) 
Last aclaris therapeutics, inc. earnings: 2/25 04:01 pm Check Earnings Report
US:NASDAQ Investor Relations: aclaristx.com
Company Research Source: Yahoo! Finance
WAYNE, Pa., Jan. 27, 2026 (GLOBE NEWSWIRE) -- Aclaris Therapeutics, Inc. (NASDAQ: ACRS), a clinical-stage biopharmaceutical company focused on developing novel product candidates for immuno-inflammatory diseases, today announced recent positive preclinical results from its potent and selective ITK/JAK3 inhibitor ATI-2138 in a murine model of severe alopecia areata (AA). In this model of hair loss, conducted by Dr. Angela Christiano at Columbia University, ATI-2138 demonstrated rapid, near complete, and sustained hair regrowth compared to control and ritlecitinib. “ATI-2138 is a potent and selective inhibitor of ITK and JAK3 with dual pharmacology that has been demonstrated to downregulate Th1, Th2, Th17, TCR (ITK) and fibrosis pathway markers, and reduce itch; this makes it an excellent mechanistic fit in a variety of I&I diseases, including across the spectrum of inflammatory alopecias?,” said Dr. Roland Kolbeck, Chief Scientific Officer of Aclaris. “The mice used in this model of Show less Read more
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