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Stock impact report

Acrivon Therapeutics Conference Highlights ACR-368 Phase 2B Data, 52% ORR in Serous Endometrial Cancer [Yahoo! Finance]

Acrivon Therapeutics, Inc. (ACRV) 
Company Research Source: Yahoo! Finance
74%, clinical benefit 65%), compared with a 22% response rate in non-serous tumors; the biomarker-positive intent-to-treat group had a 39% ORR and 81% DCR. The study uses Acrivon's OncoSignature protein-based biomarker to prospectively select patients: biomarker-positive patients received ACR-368 monotherapy while biomarker-negative patients received ACR-368 plus ultra-low-dose gemcitabine, with a lower ORR (26%) in the biomarker-negative group suggesting predictive value. The trial is expanding with a biopsy-independent serous cohort (Arm 3) to enroll up to 90 serous patients (=2 prior lines), opening at 20 European sites with expected enrollment start in early Q2 and a target to complete enrollment by end Q3; Arm 3 allows prior ADC therapy and Acrivon remains in active dialogue with the FDA. Interested in Acrivon Therapeutics, Inc.? Here are five stocks we like better. Acrivon Therapeutics (NASDAQ:ACRV) hosted a webcast featuring a key opinion leader (KOL) panel focused on t Show less Read more
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