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Stock impact report

ADC Therapeutics Eyes ZYNLONTA Expansion as LOTIS-5 Data Nears at H.C. Wainwright Chat [Yahoo! Finance]

ADC Therapeutics SA Common Shares (ADCT) 
Company Research Source: Yahoo! Finance
top-line data due in Q2 and a potential supplemental BLA filing ~4–5 months after the readout that could lead to approval around mid-2027 if positive. Early combination data from Phase Ib LOTIS-7 (ZYNLONTA + glofitamab) showed a 90% overall response rate and 78% complete response rate in 49 evaluable patients, with reduced cytokine release syndrome (~25% all-grade at the approved dose) and 100-patient data expected by year-end. Commercially, third-line ZYNLONTA sales have been variable but roughly stable (Q4 $22.3M); management says second-line approval could expand the addressable population by ~12,000 patients and drive revenue toward the $200–$300M range, while $261M in cash should fund operations into 2028. Interested in ADC Therapeutics SA? Here are five stocks we like better. ADC Therapeutics (NYSE:ADCT) executives used a recent fireside chat at the H.C. Wainwright conference to outline the company's strategy to expand the reach of its CD19-directed antibody-drug conjuga Show less Read more
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