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Stock impact report

Agios Pharmaceuticals Stock Declines 23% in 6 Months: Here's Why [Yahoo! Finance]

Agios Pharmaceuticals, Inc. (AGIO) 
Last agios pharmaceuticals, inc. earnings: 4/30 07:00 am Check Earnings Report
US:NASDAQ Investor Relations: investor.agios.com/investor-overview
Company Research Source: Yahoo! Finance
Shares of Agios Pharmaceuticals AGIO have plunged 23% over the past six months, primarily due to pipeline and regulatory setbacks, which have dampened investor confidence in the company's near-term growth prospects. Agios Pharmaceuticals currently derives revenues solely from its lead drug, mitapivat. The drug is approved for the treatment of hemolytic anemia in adult patients with pyruvate kinase (PK) deficiency under the brand name Pyrukynd. AGIO is also developing mitapivat as a potential therapy for sickle cell disease (SCD) and thalassemia indications. Over the past year, the stock has lost 8.8% against the industry's 12.7% growth. Zacks Investment Research Image Source: Zacks Investment Research Mixed Phase III Data on Mitapivat Study in SCD Reduced Confidence in AGIO In November 2025, the company reported mixed top-line data from the phase III RISE UP study, which evaluated orally administered mitapivat in patients aged 16 years or older with SCD. While the study Show less Read more
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