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0.252433090024331 0.218521897810219 0.219130170316302 0.269768856447688 0.00364963503649612 -0.0316301703163019 0.0553527980535278 -0.000608272506082827
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Akari Therapeutics Highlights Preclinical Data Demonstrating Therapeutic Potential of Lead Candidate, AKTX-101, for Hard-to-Treat K-Ras Mutant Pancreatic Cancer

Akari Therapeutics Plc - American Depositary Shares (AKTX) 
US:NASDAQ Investor Relations: investor.akaritx.com/investor-relations
Company Research Source: GlobeNewswire
Data highlights the ability of Akari’s Trop2 ADC, AKTX-101, to kill K-Ras G12V mutated cancer cell lines in preclinical models, potentially addressing one of the most lethal cancers with the lowest survival rates  The K-Ras G12V mutation is the oncogenic driver for 1/3 of all pancreatic ductal adenocarcinoma (PDAC), the most common form of pancreatic cancer Significant unmet need in pancreatic cancer where median overall survival (OS) is 1.4 years1 TAMPA, Fla. and LONDON, Dec. 09, 2025 (GLOBE NEWSWIRE) -- Akari Therapeutics, Plc (Nasdaq: AKTX), an oncology biotechnology company developing novel payload antibody drug conjugates (ADCs), today announced key preclinical data demonstrating the therapeutic potential of its novel ADC targeting Trop2, AKTX-101, in pancreatic cancer driven by K-Ras mutations, one of the deadliest and most treatment-resistant forms of cancer. Pancreatic cancer is one of the most lethal malignancies, characterized by its typically late-stage diagnosis, res Show less Read more
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