Albireo Completes Enrollment in Phase 2 Study of Elobixibat in NASH/NAFLD
Albireo Pharma, Inc. (ALBO)
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Source: GlobeNewswire
On track to report topline data mid-2020 BOSTON, March 10, 2020 (GLOBE NEWSWIRE) -- Albireo Pharma, Inc. (Nasdaq: ALBO), a clinical-stage orphan pediatric liver disease company developing novel bile acid modulators, today announced achievement of full patient enrollment in its Phase 2 clinical trial of elobixibat 5mg, a first-in-class, once-daily, orally available ileal bile acid transporter (IBAT) inhibitor for the treatment of nonalcoholic steatohepatitis (NASH) and nonalcoholic fatty liver disease (NAFLD). Albireo is on track to report topline results in mid-2020. Albireo expects results from a second NASH/NAFLD trial with elobixibat, sponsored by its Japanese partner EA Pharma, late this year or early next year. These two proof-of-concept studies are designed to assess the combination of improvements in liver function and cardiovascular risk parameters with a favorable gastrointestinal tolerability profile. The combined data from both studies will inform next steps for Albireo
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