Alector Showcases ABC Brain-Delivery Platform, AL137 and AL050 Updates at TD Cowen Conference [Yahoo! Finance]
Alector, Inc. (ALEC)
Last alector, inc. earnings: 3/24 04:05 pm
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Source: Yahoo! Finance
substantially higher brain uptake in nonhuman primates while reducing Fc-mediated safety liabilities like sustained reticulocyte depletion versus more exposed TfR epitopes. AL137 , an ABC-enabled anti-amyloid antibody, produced 12-fold higher CSF levels and ~30-fold higher parenchymal brain levels versus a non-ABC antibody in NHPs, was well tolerated, and is being pushed toward an IND by year-end/early next year with first-in-human SAD/MAD studies (including a subcutaneous arm) planned to read out amyloid PET effects. ABC-enabled AL050 and siRNA programs demonstrate platform versatility: AL050 is an engineered GCase (~50x activity, much greater stability) that increased brain enzymatic activity and uptake in NHPs with good tolerability, and ABC-delivered siRNA showed up to ~70% tau mRNA knockdown and sustained CSF tau reductions after peripheral dosing in primate studies. Interested in Alector, Inc.? Here are five stocks we like better. These biotechs targeting multiple neurod
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ALEC
News
- Alector (ALEC) was downgraded by <a style="font-weight:bold" href="https://www.wallstreetzen.com/newsletters/zen-ratings?ticker=ALEC&utm_campaign=getratings&utm_medium=online&utm_source=MarketBeat">Wall Street Zen</a> from "hold" to "sellMarketBeat
- Alector Reports Fourth Quarter and Full Year 2025 Financial Results and Provides Business UpdateGlobeNewswire
- Alector to Participate in the TD Cowen 46th Annual Health Care ConferenceGlobeNewswire
- INVESTOR ALERT: Levi & Korsinsky is Investigating Alec Stock After its Phase 3 INFRONT-3 Clinical Trial Misses Co-Primary EndpointPR Newswire
- Alector (NASDAQ:ALEC) had its "underweight" rating reaffirmed by analysts at Morgan Stanley.MarketBeat
ALEC
Earnings
- 2/25/26 - Beat
ALEC
Sec Filings
- 3/3/26 - Form 4
- 3/3/26 - Form 144
- 3/3/26 - Form 4
- ALEC's page on the SEC website