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Allogene Therapeutics Teases April ALPHA3 Futility Data, Details Autoimmune CAR-T Program at TD Cowen [Yahoo! Finance]

Allogene Therapeutics, Inc. (ALLO) 
Last allogene therapeutics, inc. earnings: 2/27 04:30 am Check Earnings Report
Company Research Source: Yahoo! Finance
based on MRD clearance in 24 patients , with a prespecified bar of an absolute 25–30% MRD clearance improvement for cema-cel versus observation; the randomized ~220-patient study uses event-free survival as the primary endpoint. Management says its "Allogene XL" allogeneic CAR-T can be manufactured at “biologic-like” scale (~ 20,000–60,000 doses/year ) with estimated cost of goods of $10,000–$20,000 per dose, and frames a commercial opportunity of ~ MRD-positive/insufficiently treated patients in the U.S. and Europe (~ $5 billion TAM) with potential peak sales well over $2 billion The autoimmune program ALLO-329 is a dual CD19/CD70 "Dagger" allogeneic CAR-T designed to enable lighter or no lymphodepletion (starting at 20M cells with Cy-only and no-LD cohorts), with initial proof-of-concept and biomarker readouts expected in June 2026 Interested in Allogene Therapeutics, Inc.? Here are five stocks we like better. 3 Stocks With Sky-High Short Interest Levels Allogene Therapeut Show less Read more
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