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-0.000128423283141299 -0.000449481490994456 -0.00202266670947441 -0.00338716409285006 0.000898962981988547 0.00940700549009538 0.00940700549009538 0.00940700549009538
Stock impact report

Alnylam Hit Hard As Investors Forced To Revise Future Profit Expectations [Seeking Alpha]

Alnylam Pharmaceuticals, Inc. (ALNY) 
Last alnylam pharmaceuticals, inc. earnings: 2/6 08:00 am Check Earnings Report
US:NASDAQ Investor Relations: investors.alnylam.com/investor-overview
Company Research Source: Seeking Alpha
The TTR business will likely remain "noisy" in the first half of 2026, but Amvuttra continues to gain share, and management guidance for 2026 was above expectations. Management alarmed the Street earlier this year with long-term spending guidance that was considerably higher than expected; management continues to prioritize R&D to realize the company's full long-term potential. 2026 is a 'sleeper year' for clinical data, but early-stage readouts from ALN-6400, ALN-HTT02, and ALN-2232 could provide upside catalysts. Fair value now stands at $456 per share, with about 70% of that tied to the TTR franchise, but meaningful longer-term upside is tied to positive clinical trial readouts. anusorn nakdee/iStock via Getty Images It's been a rough go for Alnylam Pharmaceuticals ( ALNY ) since October 2025, with the shares down almost 40% from an all-time high. While it is typically clinical failures that hit biotechs hard, Alnylam is in that awkward biopharma adolescence where invest Show less Read more
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